What Factors Influence the Success of IVF on the First Try?

Reviewed By: Dr. Shruthi Mantri, a fertility specialist at Ferty9 Fertility Center, LB Nagar, Hyderabad

In vitro fertilisation (IVF) journey can be an emotional and life-altering decision for couples struggling with fertility issues. While IVF offers hope for conception, the success rates can vary depending on various factors. Knowing these factors helps couples in making informed decisions & increases their chances of achieving a successful pregnancy on their first IVF attempt.

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How Does IVF Work?

IVF is an assisted reproductive technology (ART). It involves getting eggs from a female's ovaries & fertilising them with sperm in a laboratory. The fertilised eggs, known as embryos, are then transferred into the woman's uterus, where they can implant and develop into a pregnancy. This process bypasses the fallopian tubes, making it a practical option for couples with various fertility issues.

Suggested Read: What Are the Different Types of IVF Treatments Available?

Reasons for IVF Failure on the First Try?

Despite the advancements in IVF technology, the success rates can vary, and some couples may not achieve a successful pregnancy on their first attempt. Several factors can contribute to IVF failure, including:

• Poor egg or embryo quality
• Inadequate sperm quality
• Uterine factors, such as fibroid tumours or abnormalities
• Underlying medical conditions
• Advanced maternal age
• Unhealthy lifestyle factors, such as smoking or excessive alcohol consumption
• Improper embryo transfer technique

Understanding the potential reasons for failure can help couples and their doctors make informed decisions and adjust their approach for subsequent IVF cycles.

Suggested Read: What is IVF? Step-by-Step Guide to the IVF Process

What Factors Impact the Success of IVF?

Several factors influence the success of IVF on the first try. Let's explore each of these factors in detail:

Quantity and quality of the eggs/embryo

The quality & quantity of eggs retrieved during the IVF process plays a crucial role in determining the success rates. Women with a higher number of high-quality eggs have a better chance of producing viable embryos, increasing the likelihood of a successful pregnancy.

Quantity and quality of sperm

Sperm quality is another critical factor that can impact IVF success. Poor sperm motility, concentration, or morphology can hinder fertilisation and embryo development, reducing the chances of a successful pregnancy.

Age of the Woman

A woman's age is a significant component in determining IVF success rates. As women grow older, their ovarian reserve (the number of remaining eggs) decreases, and the quality of the eggs may decline. Generally, women under the age of 35 have higher success rates compared to those over 40.

Genetic Factors

Genetic factors can play a role in IVF success. Chromosomal abnormalities or genetic disorders in either partner can affect embryo development and implantation, reducing the chances of a successful pregnancy.

Overall Health and Lifestyle

A woman's overall health and lifestyle can influence IVF outcomes. Factors such as obesity, smoking, excessive alcohol consumption, and certain medical conditions like endometriosis or polycystic ovarian syndrome (PCOS) can negatively impact IVF success rates.

IVF Clinic and Technology

The experience and expertise of the IVF clinic, as well as the technology and techniques used, can significantly impact success rates. Clinics with state-of-the-art equipment, experienced embryologists, and a track record of successful outcomes can increase the chances of a successful first IVF cycle.

Embryo Transfer Technique

The embryo transfer technique is a critical step in the IVF process. Proper positioning of the embryo within the uterus and minimising trauma during the transfer can improve the chances of successful implantation and pregnancy.

Timing of Ovulation

Accurately timing ovulation is crucial for IVF success. Precise monitoring of hormone levels and follicular development can help determine the optimal time for egg retrieval and embryo transfer, increasing the chances of a successful pregnancy.

Mental and Emotional Well-Being

The emotional & psychological stress associated with infertility and IVF treatment can impact success rates. Stress, anxiety & depression can affect hormone levels and potentially hinder the body's ability to respond to treatment. Seeking emotional support and practising stress-management techniques can be beneficial.

Suggested Read: Managing Stress through Counselling and Support

How to Increase First-time IVF Success Rates

While some factors are beyond control, there are steps people can take to improve success on their first IVF attempt:

• Maintain a Healthy Lifestyle: Adopt a balanced diet, exercise regularly & avoid smoking and excessive alcohol. These healthy lifestyle changes can improve overall health and increase the chances of a successful pregnancy.
• Seek Counselling and Support: Undergoing IVF can be emotionally and mentally taxing. Seeking counselling or joining support groups can help manage stress and provide emotional support throughout the process.
• Communicate with Your Doctor: Open communication with your fertility specialist is crucial. Discuss your concerns, ask questions, and follow their recommendations to optimise your chances of success.
• Consider Preimplantation Genetic Testing (PGT): PGT can screen embryos for genetic abnormalities, increasing the chances of selecting viable embryos for transfer and reducing the risk of miscarriage or genetic disorders.
• Explore Complementary Therapies: While scientific evidence is limited, some complementary therapies, such as acupuncture or mind-body techniques, may reduce stress & improve overall well-being during the IVF process.

Suggested Read: Essential Insights: 10 Must-Know Facts About IVF

Ferty9 Counselling Sessions for First-time IVF Success

At Ferty9, we understand the emotional and psychological challenges associated with infertility and IVF treatment. Our experienced counsellors offer personalised counselling sessions to support couples throughout their IVF journey. These sessions can help manage stress and anxiety and provide coping strategies, ultimately increasing the chances of a successful first IVF cycle.

If you're considering IVF or are currently undergoing treatment, we encourage you to schedule a counselling session with Ferty9. Our compassionate counsellors are here to guide and support you every step of the way.

Conclusion

The success of IVF on the first try depends on a multitude of factors, including the quality and quantity of eggs & sperm, the woman's age, overall health, and the expertise of the fertility clinic. While we cannot control some of these factors, adopting a healthy lifestyle, seeking emotional support, and communicating openly with doctors can increase the chances of a successful outcome.

Remember, every individual's journey is unique, and even if the first IVF attempt is unsuccessful, there are still opportunities for future cycles. With perseverance, guidance from doctors, and a positive mindset, many couples can overcome fertility challenges and achieve their dream of starting a family.

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